Prevention of lung cancer progression by bexarotene in mouse models
نویسندگان
چکیده
منابع مشابه
Cancer Prevention Research Preventive Effects of Bexarotene and Budesonide in a Genetically Engineered Mouse Model of Small Cell Lung Cancer
In the present study, we examined the effect of bexarotene (Targretin) and budesonide in the chemoprevention of small cell lung carcinoma using a lung-specific knockout model of Rb1 and p53. Upon treatment with bexarotene, tumor incidence, number, and load were significantly reduced (P < 0.05). Budesonide treatment trended to inhibition, but the effect was not statistically significant (P > 0.0...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2005
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1209180